Hormone Therapy for Men and Women

At ManUp / WomanUp, we are proud to be one of the first clinics in the St. Louis region to specialize in hormone replacement therapy (HRT) for both men and women. With five convenient locations in O’Fallon, St. Peters, Ellisville, Fenton, and Washington, MO, our mission is to help patients restore hormonal balance, improve their overall health, and achieve lasting vitality.

Hormone therapy is not just about correcting numbers on a lab test—it’s about reclaiming your quality of life. For many people, subtle but persistent issues such as fatigue, weight gain, irritability, brain fog, or low libido are signals that hormones may be out of balance. Left untreated, these symptoms can hold you back from feeling and performing your best.

Through advanced diagnostic testing, personalized treatment protocols, and ongoing support, ManUp and WomanUp are committed to guiding patients on their journey from feeling suboptimal to thriving in every area of life.

Why Hormones Matter for Your Health

Hormones are the body’s chemical messengers, controlling countless functions that affect how you look, feel, and perform each day. They regulate metabolism, energy levels, mood, cognitive clarity, sexual health, and muscle development. When hormone levels decline or shift, even small imbalances can ripple into major changes in your well-being.

Signs of Hormonal Imbalance in Men and Women

Some of the most common symptoms include:

  • Persistent fatigue and lack of energy

  • Difficulty losing weight or unexpected weight gain

  • Decreased muscle mass or strength

  • Low libido and sexual dysfunction

  • Poor sleep and disrupted recovery

  • Mood swings, anxiety, or irritability

  • Cognitive “fog” or difficulty focusing

These issues are not just inconveniences—they are biological signals that your body may not be operating in balance. The good news is that with proper hormone evaluation and treatment, these symptoms are not permanent.

Our Comprehensive Approach to Hormone Therapy

At ManUp / WomanUp, hormone therapy is not a one-size-fits-all solution. We start with a deep understanding of your medical history, lifestyle, goals, and advanced bloodwork to create a tailored treatment plan.

Our providers use a variety of proven therapies, including injectable and oral forms of testosterone (for men) and bioidentical hormone replacement therapies (for women), alongside nutritional guidance, peptide therapies, and supplementation when needed.

This integrated approach ensures that each patient receives care that is safe, effective, and designed to optimize both internal biomarkers and external results.

The Four Phases of Wellness Transformation

Every patient’s journey is unique, but over years of experience, we’ve identified four common phases of transformation. These stages help patients and providers align expectations, set goals, and celebrate progress along the way.

Phase 1: Restoring Balance

Phase 1 is where most patients begin. You may be feeling off balance—tired, stressed, gaining weight, or struggling with sexual health. The goal at this stage is to identify deficiencies, restore hormonal balance, and get your body back to a healthier baseline.

During Phase 1:

  • We run comprehensive labs to evaluate your hormone levels and related biomarkers.

  • We design a personalized treatment plan to address deficiencies and restore balance.

  • Most patients begin to feel noticeable improvements in energy, sleep, and mood within weeks.

This phase is about stopping the decline and beginning to feel like yourself again.

Phase 2: Achieving Optimal Health

Once your hormone levels are restored, Phase 2 focuses on reaching and maintaining optimal health markers. At this point, many patients have:

  • Balanced mood and energy

  • Healthy weight loss trends

  • Improved libido and sexual function

  • Better sleep quality

  • Sharper focus and reduced “brain fog”

Patients in Phase 2 often feel better than they have in years. They enjoy stable wellness, improved confidence, and an overall sense of vitality. Many choose to maintain this level long term, while others look ahead to building a stronger, fitter body composition.

Phase 3: Building a Fitter, Stronger Body

Phase 3 is about taking your wellness to the next level. You’re already balanced on the inside, but now you want your external results to reflect your hard work. Patients in this phase focus on achieving:

  • A leaner, more athletic body composition

  • Greater muscle development and definition

  • Lower body fat percentages

  • Enhanced strength and physical performance

With optimized hormone therapy protocols, when combined with appropriate training and nutrition, patients see transformational physical changes—moving beyond “healthy” to looking and feeling “fit.”

Phase 4: Reaching Peak Human Performance

Phase 4 is for those who want to push the limits of physical and aesthetic performance. Representing a smaller but highly motivated group of patients, Phase 4 combines the foundation of hormone balance with advanced peptide therapies, precision supplementation, and strategic treatment adjustments.

Patients in this stage often aspire to:

  • Achieve elite-level body composition

  • Maximize muscle growth while maintaining low body fat

  • Speed up recovery and enhance resilience

  • Unlock their body’s highest performance potential

At ManUp / WomanUp, Phase 4 is always pursued safely, with careful monitoring of biomarkers to ensure peak performance is balanced with long-term health.

Why Choose ManUp / WomanUp?

We understand that patients in the St. Louis region have choices when it comes to hormone therapy. Here’s what sets us apart:

  • Experience & Leadership – As one of the earliest clinics in the St. Louis area to focus on HRT, we’ve helped thousands of men and women transform their lives.

  • Comprehensive Care – We don’t just “prescribe hormones.” We integrate lab analysis, personalized protocols, nutrition, peptides, and lifestyle support.

  • Five Locations – Conveniently located in O’Fallon, St. Peters, Ellisville, Fenton, and Washington, MO.

  • Patient-First Philosophy – Every plan is custom-built around your goals, not a generic template.

  • Whole-Body Results – From energy and focus to muscle, metabolism, and sexual health, we help you improve every dimension of wellness.

Patient Success Stories

Our patients often describe hormone therapy as “life-changing.” Whether it’s a busy professional regaining focus, a parent reclaiming energy to keep up with family, or an athlete striving for peak performance, the stories share a common theme: hormone therapy restores possibilities that once felt out of reach.

Start Your Hormone Therapy Journey Today

Whether you’re in Phase 1, just starting to feel “off,” or aiming for Phase 4 peak performance, ManUp / WomanUp has the expertise and resources to guide you.

Explore our gender-specific programs:

Take the first step today. Schedule a consultation at one of our five St. Louis-area locations and discover how hormone therapy can help you:

  • Restore balance and vitality

  • Achieve optimal health and wellness

  • Build a stronger, fitter body

  • Unlock your highest potential

At ManUp / WomanUp, we don’t just treat hormones—we help you transform your life.