WHY CHOOSE

(SPECIALTY) PHYSICIAN MONITORED?

You wouldn’t take your car to someone who wasn’t a a qualified mechanic, why would you trust your healthcare with someone who isn’t a doctor?

LEGALITY

  • The most obvious reason to choose a qualified physician to monitor your testosterone therapy. If you are taking testosterone that you get from a non-physician source, you are breaking the law and could face criminal charges for possessing a controlled substance.

SIDE EFFECTS

  • If not monitored by a qualified physician, testosterone therapy can produce unwanted side effects and pose serious health risks. When a qualified physician monitors your treatment, these side effects can be avoided with simple routine blood work. Unmonitored side effects can include but are not limited to acne, irritability/aggression, mood swings, hair loss, nipple tenderness, testicle shrinkage, and even stroke.

ROUTINE LEVEL CHECKS AND DOSING ADJUSTMENTS

  • When a qualified testosterone specialist physician monitors your treatment, you will have routine blood work done to assure that, along with keeping track of your symptoms, your testosterone level is increasing, and your other hormones are being properly balanced to avoid side effects. Dosing may need to be increased or decreased depending on your symptoms and levels.

COSTS TO BENEFITS

  • Your primary care can only do so much within the guidelines of insurance, because we dont work through insurance, we can create the most affordable way for you to notice and maintain results.

OTHER SERVICES

  • We can recommend other treatments that can work with testosterone optimization therapy depending on what your goals are that can help you reach your health and fitness goals faster and more effectively. To Everything

Why Optimizing Testosterone Levels Matters for Men’s Health

Reclaim Strength, Drive, and Vitality with Testosterone Optimization

As men age, testosterone levels naturally begin to decline—often starting as early as their 30s. This drop in hormones can lead to low energy, reduced sex drive, muscle loss, brain fog, and a range of other health issues that impact your performance, confidence, and overall quality of life.

At ManUP Testosterone Clinic, we specialize in helping men take back control of their health through testosterone optimization therapy (TOT). Whether you’re feeling tired, foggy, or just not like yourself, it’s time to explore how optimized testosterone levels can change your life.

What Is Testosterone and Why Is It So Important?

Testosterone is the primary male sex hormone responsible for:

  • Muscle growth and fat metabolism

  • Energy production and stamina

  • Mental clarity and mood regulation

  • Libido and sexual function

  • Bone strength and cardiovascular health

When testosterone levels fall below optimal ranges, you may feel it in every aspect of your life—from your morning routine to your relationships and performance at work.

8 Life-Changing Benefits of Testosterone Optimization

1. Boosts Energy and Reduces Fatigue

Chronic tiredness and low motivation are classic signs of low testosterone. Optimizing your levels can restore your energy, increase stamina, and help you power through your day without burnout.

2. Builds Lean Muscle & Burns Fat

Testosterone is a critical hormone for maintaining muscle mass and controlling body fat. When optimized, you’ll find it easier to gain lean muscle, increase strength, and shed stubborn belly fat—especially when paired with proper nutrition and strength training.

3. Enhances Mental Focus & Reduces Brain Fog

If you’ve been struggling with forgetfulness, poor concentration, or mental sluggishness, low testosterone might be the reason. Optimization improves cognitive function, enhances memory, and restores the mental sharpness you once had.

4. Improves Mood and Emotional Stability

Mood swings, irritability, and even depression are commonly linked to low testosterone. Restoring optimal levels helps stabilize your mood, reduce anxiety, and boost overall emotional well-being.

5. Revitalizes Libido and Sexual Performance

Low testosterone is a common cause of reduced sex drive and erectile dysfunction. With optimized testosterone levels, men often experience increased desire, improved performance, and renewed confidence in their relationships.

6. Supports Heart and Cardiovascular Health

Testosterone helps regulate blood flow, red blood cell production, and cholesterol levels. Studies suggest that optimized levels may reduce the risk of heart disease, improve circulation, and support long-term heart health.

7. Strengthens Bones and Joints

As testosterone declines, bone density decreases, increasing the risk of fractures and joint pain. Testosterone optimization helps protect your skeletal structure, preventing age-related conditions like osteoporosis.

8. Reduces Risk of Chronic Disease

Low testosterone is linked to higher rates of:

  • Type 2 diabetes

  • Metabolic syndrome

  • Obesity

  • Inflammatory disorders

Optimizing testosterone improves insulin sensitivity, regulates metabolism, and helps you maintain a healthier weight—reducing your long-term disease risk.

Before beginning testosterone therapy, it’s crucial to have a clear understanding of your current health status through a series of essential blood tests. These tests will help ensure that the therapy is safe and effective for you. Here are the key blood tests commonly required:

1. Complete Blood Count (CBC)

A CBC provides a comprehensive overview of your blood health. It measures red and white blood cells, hemoglobin, hematocrit, and platelets, helping to identify any underlying conditions such as anemia or infections.

2. Metabolic Profile

This test assesses kidney and liver function, electrolyte balance, and glucose levels. It’s vital for evaluating your overall metabolic health and ensuring that your body can handle testosterone therapy.

3. Lipid Panel

A lipid panel measures cholesterol levels, including LDL, HDL, and triglycerides. Monitoring these is important because testosterone therapy can impact cardiovascular health.

4. Prostate-Specific Antigen (PSA)

For those at risk of prostate issues, a PSA test is important to rule out prostate cancer and monitor prostate health during therapy.

5. Testosterone Levels

Both total and free testosterone levels need to be assessed. This gives a baseline understanding of your hormone levels and helps tailor the therapy to your specific needs.

These tests not only guide the initiation of testosterone therapy but also help monitor any changes throughout the treatment process. Always consult with your healthcare provider to ensure the tests are comprehensive and tailored to your individual health profile.

Embarking on testosterone therapy involves a series of important steps to ensure that the treatment is appropriate and effective for you. Here’s how you can begin:

1. Schedule an Initial Consultation

The first step is to meet with a healthcare provider. During this visit, your doctor will:

  • Review your medical history and any existing health conditions.
  • Discuss your family’s medical history, particularly about hormone-related issues.
  • Evaluate your current medications to avoid any adverse interactions.
  • Identify and discuss the symptoms you’re experiencing that might suggest low testosterone levels.

2. Undergo Comprehensive Blood Testing

Your doctor will recommend several key blood tests to assess your hormone levels and overall health:

  • Complete Blood Count (CBC): This test checks your general health status and detects a variety of disorders.
  • Metabolic Panel: Assesses your body’s chemical balance and metabolism.
  • Lipid Profile: Measures your cholesterol and triglycerides.
  • Prostate-Specific Antigen (PSA): Essential, especially for men, to rule out prostate issues.
  • Testosterone Levels: Measures both total and free testosterone to understand deficiency levels accurately.

3. Discuss Treatment Options

Once the test results are in, your healthcare provider will:

  • Review the lab results with you in detail.
  • Discuss different treatment strategies tailored to your specific needs.
  • Initiate the chosen therapy plan, which might include medications, lifestyle changes, or potentially both.

4. Follow-Up Visits

Continuous monitoring is crucial for assessing the therapy’s effectiveness and making any necessary adjustments:

  • After approximately three months, repeat lab tests to monitor your progress is mandatory.
  • Arrange a follow-up visit with your healthcare provider about four months after starting therapy. This face-to-face meeting allows for a comprehensive evaluation of your symptoms and progress.

By following these steps, you’ll be well-prepared to begin testosterone therapy under professional guidance, ensuring safety and effectiveness throughout the process.

When undergoing testosterone therapy, many men often wonder how long it will take to notice improvements in sexual health, particularly concerning erectile dysfunction and ejaculation.

Short-Term Improvements

  • Initial Changes: You might begin to observe some positive effects within the first three to four weeks. These early changes can include increased energy levels and mood enhancements, which can indirectly support sexual health.

Long-Term Adjustments

  • Erectile Dysfunction: Significant improvements in erectile function may take longer—often up to six months. Consistent therapy is crucial, as this timeline allows the body to adjust gradually and effectively.
  • Ejaculation Issues: Similar to erectile dysfunction, changes in ejaculation may also require up to six months to reach noticeable improvement.

Keep in mind that individual responses can vary based on multiple factors, including age, overall health, and specific therapy protocols. It’s important to maintain open communication with your healthcare provider to tailor the best treatment plan for your needs.

When undergoing testosterone therapy, implementing specific lifestyle changes can significantly amplify the results. Here are some strategies to consider:

Prioritize Quality Sleep

  • Aim for 7 to 9 hours of restorative sleep per night. Consistent, quality sleep supports hormone regulation and overall well-being.

Commit to Regular Exercise

  • Engage in physical activity 5 to 7 days a week. Incorporate both strength training and cardiovascular exercises to boost energy levels and muscle mass.

Maintain a Healthy Digestive System

  • Ensure regular bowel movements—targeting 1 to 3 times a day—by consuming adequate fiber and staying hydrated.

Embrace Clean Eating

  • Focus on a balanced diet rich in whole foods. Prioritize vegetables, lean proteins, and healthy fats while minimizing processed foods and added sugars.

Plan for Detoxification

  • Consider detoxifying your body twice a year to help eliminate toxins and improve metabolic functions. Consult with a healthcare professional for safe and effective methods.

Support Thyroid Health

  • Monitor and maintain optimal thyroid function, as it plays a crucial role in metabolic balance and energy levels. Regular check-ups with your healthcare provider can help ensure your thyroid is functioning correctly.

Our overarching aim is to support your journey towards better health and vitality. A balanced approach involving nutrition, weight management, and regular exercise can significantly enhance your therapy outcomes.

Testosterone therapy can significantly enhance well-being and resolve various symptoms. However, its effectiveness is closely linked to lifestyle choices, particularly sleep, exercise, and diet.

The Power of Sleep

Quality sleep—ideally 7 to 9 hours per night—serves as a foundation for effective testosterone therapy. Restorative sleep helps balance hormones and supports the body’s natural healing processes. Inadequate sleep can disrupt testosterone levels, counteracting the benefits of therapy. Prioritizing sleep aids in quicker symptom improvement and can enhance overall mood and energy levels.

Exercise as a Catalyst

Regular physical activity—aiming for 5 to 7 days a week—plays a crucial role in maximizing the outcomes of testosterone therapy. Exercise enhances blood circulation, boosts mood, and stimulates muscle growth, all of which can amplify the therapy’s effects. Engaging in a mix of aerobic and resistance training can lead to improved stamina and vitality. Moreover, consistent exercise aids weight management, which is crucial for maintaining balanced hormone levels.

Diet’s Influence

Diet is another significant factor in optimizing testosterone therapy. A clean, balanced diet rich in whole foods provides essential nutrients that support hormonal health. Foods high in zinc, vitamin D, and omega-3 fatty acids—like nuts, leafy greens, and fish—can further bolster testosterone production. Avoiding processed foods and sugars not only aids weight management but also helps maintain stable hormone levels, contributing to better therapy outcomes.

Additional Considerations

Beyond sleep, exercise, and diet, other elements can enhance testosterone therapy’s effectiveness. Ensuring regular digestive health and detoxifying periodically also supports optimal bodily functions. Maintaining a healthy thyroid function is particularly crucial, as it can directly impact hormone regulation.

In summary, integrating healthy habits into your lifestyle can dramatically enhance the effectiveness of testosterone therapy, leading to faster and more lasting results. By focusing on quality sleep, regular exercise, and a nutritious diet, you set the stage for optimal health and well-being.

Self-injected testosterone therapy empowers individuals to manage their hormonal health from the comfort of their own homes. This method involves injecting testosterone directly into the subcutaneous tissue—typically in areas like the thigh, abdomen, or flanks.

How It Works

  1. Preparation: Patients or their family members prepare a small needle and syringe, drawing the prescribed dosage of testosterone.
  2. Injection Sites: Common areas for injection include the thighs, love handles, or belly. These locations ensure effective absorption while minimizing discomfort.
  3. Frequency: The therapy typically requires administration two to three times weekly, ensuring consistent hormone levels.
  4. Monitoring: Regular lab work is conducted to monitor hormone levels, ensuring the therapy is effective and tailored to individual needs.

Benefits

  • Time-Efficient: There’s no need to schedule frequent visits to a healthcare provider, providing greater flexibility for busy lifestyles.
  • Enhanced Results: This method is renowned for delivering superior results, helping patients achieve optimal hormonal balance.
  • Minimal Discomfort: The process involves very little pain, making it a viable option for those intimidated by injectable therapies.
  • Safety: There is no risk of accidentally transferring the hormone to others, such as family members or pets, as can be the case with topical applications.

Self-injected testosterone therapy offers a blend of convenience, effectiveness, and safety, making it an attractive option for managing hormone levels.

When exploring fertility treatments, Clomid and hCG are two noteworthy options often used to support hormonal balance and increase reproductive potential in males.

What is hCG Therapy?

Human Chorionic Gonadotropin (hCG) is a hormone traditionally associated with pregnancy, but its application goes beyond that scope. In the context of male fertility and hormonal health, hCG is administered as an injection once to twice a week. This therapy helps maintain testicular size and promotes sperm production when an individual is undergoing testosterone therapy.

  • Purpose: Supports testicular function and sperm production.
  • Administration: Twice-weekly injections.

How does Clomid Therapy Work?

Clomid, an oral medication that is primarily approved for treating infertility in women, is also used “off label” for men. Its function in men revolves around blocking estrogen receptors in the hypothalamus. This blockage prompts the hypothalamus to secrete more GnRH (gonadotropin-releasing hormone).

  • Mechanism: Boosts GnRH, leading to increased pituitary release of LH (luteinizing hormone) and FSH (follicle-stimulating hormone).
  • Effects: Encourages the testicles to boost testosterone and sperm production.

Clomid is typically taken three times a week by mouth, offering a convenient protocol for those it benefits. However, it’s important to note that not everyone will have the same response to Clomid, and healthcare providers will often monitor its effectiveness closely.

Bioidentical hormone cream therapy is a treatment that involves the use of topically applied creams containing hormones that are chemically identical to those produced naturally by the human body. This method is often used to help balance hormone levels, particularly testosterone, which can diminish with age or certain health conditions.

Advantages of Bioidentical Hormone Cream Therapy

  • Convenience of Use: This therapy can be easily applied at home, eliminating the need for clinical visits or professional assistance.
  • Non-invasive Approach: Unlike treatments that require injections or other medical procedures, bioidentical hormone creams are simply applied to the skin, making the process pain-free.
  • Personalized Treatment: The dosage can often be adjusted based on your body’s response, ensuring a more tailored approach to hormone balancing.
  • Improved Well-being: Users often experience enhanced energy levels, mood stability, and other benefits associated with balanced hormone levels.

This treatment provides a simple and effective way to manage hormone-related issues, offering an easy-to-use alternative to more invasive methods.

Why You Shouldn’t Wait to Optimize Your Testosterone

Many men dismiss symptoms of low testosterone as simply “getting older.” The truth is, untreated hormone imbalances can gradually chip away at your quality of life and increase your risk for chronic illness.

Taking action now means:

  • Preventing further hormonal decline

  • Preserving muscle, memory, and motivation

  • Protecting long-term health and vitality

  • Reclaiming control of your body and your mindset

How ManUP Testosterone Clinic Can Help

At ManUP Testosterone Clinic, we don’t believe in cookie-cutter solutions. Our testosterone optimization programs are 100% personalized based on:

  • Lab-tested hormone levels

  • Your symptoms and health history

  • Lifestyle and performance goals

We use safe, medically-supervised testosterone therapy (injections, pellets, or topical treatments), combined with nutritional support, exercise guidance, and optional supplementation (such as HCG) to ensure your body functions at its best.

Five Convenient Locations in Missouri

Wherever you are in the St. Louis region, ManUP is close by:

  • O’Fallon, MO

  • St. Peters, MO

  • Ellisville, MO

  • Fenton, MO

  • Washington, MO

📞 Ready to Optimize Your Testosterone?

If you’re experiencing symptoms of low testosterone—or just want to perform at your highest level—it’s time to ManUP and take control of your health.

📍 Schedule your consultation today and see how our personalized testosterone therapy can help you:

  • Boost energy

  • Regain confidence

  • Improve body composition

  • Reignite your drive—for life, love, and success

Yes, many studies have shown that hormone therapy is safe when administered in the correct dosage and monitored by a qualified physician.

Some patients begin to feel the effects immediately. In general, we ask that you give the plan between 4-6 weeks for best results.

  • Testosterone Cypionate
  • Anastrozole (Estrogen Blocker)
  • Clomiphene Citrate

No, unfortunately the only way to determine if you are a candidate for testosterone replacement therapy is through a blood test.

Labs are not included in the price of the monthly TRT plan. We can either give you a cash price for labs or we can use your insurance for lab work.

We require blood work every 8 weeks. The 8-week labs are very important to determine how the patient is responding to the medication and to assess if any changes need to be made to your treatment plan.

If you provide your own labs, they can be no older than 90 days. Patients transferring from another TRT clinic can provide us with labs up to 5 months old since they have already established therapy with a prior physician.

This depends on where your levels are at that time. If you are transferring from another TRT clinic we would expect your levels to be elevated. Unless your testosterone levels are above 1250, it should never be requested of a patient already on TRT to plummet their levels just to transfer to another clinic.