TRT Dosage Guide: How to Find Your Ideal Testosterone Dose

Personalized Testosterone Therapy for Optimal Results

At ManUP Testosterone Clinic, we understand that Testosterone Replacement Therapy (TRT) is not a one-size-fits-all solution. Your ideal testosterone dosage depends on a variety of personal factors—age, metabolism, lifestyle, baseline hormone levels, and your body’s response to treatment.

Getting the correct weekly TRT dosage is critical. Too low, and you may see little to no improvement. Too high, and you risk side effects like mood swings, water retention, or hormone imbalances. That’s why we tailor every treatment plan based on clinical data, symptoms, and how you feel over time.

Why TRT Dosage Accuracy Matters

Testosterone plays a key role in male health—it regulates energy, muscle mass, libido, cognition, and emotional stability. But just boosting testosterone levels isn’t enough. The goal of testosterone therapy is hormone optimization, not just hormone replacement.

Finding the correct dose of testosterone per week helps you:

  • Alleviate symptoms of low testosterone

  • Maintain safe, stable hormone levels

  • Avoid unwanted side effects

  • Improve long-term physical and mental health

At ManUP, we help you fine-tune your TRT plan for sustainable results.

Common TRT Delivery Methods and Dosage Ranges

Testosterone Injections
The most popular and effective form of TRT. Injections offer quick results and flexible dosing.

  • Typical starting dose: 100–200 mg per week of testosterone cypionate or enanthate

  • Frequency: Weekly or biweekly, sometimes split into smaller doses

  • Dose adjustments: Based on lab work and how you feel

Topical Gels and Creams
A needle-free, daily option for men who prefer convenience.

  • Dose: 50–100 mg applied to the skin daily

  • Application: Usually on the upper arms, shoulders, or abdomen

  • Consistency: Must be applied daily to maintain hormone levels

Testosterone Pellets
Pellets are inserted under the skin and release testosterone slowly over time.

  • Duration: Typically lasts 3 to 6 months

  • Dose: Customized by provider based on body size and hormone needs

  • Advantage: Fewer fluctuations, minimal maintenance

Oral Testosterone
Oral options are available for those who prefer to avoid injections or topical applications.

  • Common dose: 400–800 mg daily, split into two doses with food

  • Absorption: Works best with a high-fat meal

  • Consideration: May not be suitable for all due to liver metabolism

Key Factors That Affect Your TRT Dosage

Determining the right TRT dose isn’t just about age or weight. Your body’s hormonal needs are influenced by several unique factors:

Age and Metabolism
Older men typically metabolize testosterone more slowly, which means smaller doses may still be effective.

Body Composition
Men with a higher BMI often require slightly higher doses. Body fat influences testosterone production and absorption.

Baseline Hormone Levels
Your starting testosterone levels are essential in determining your initial dosing protocol. More severe deficiencies may require higher starting doses.

Lifestyle and Stress Levels
Diet, exercise, sleep, and stress can all affect how your body responds to TRT. Active men may metabolize testosterone more efficiently.

Treatment Response
Your symptoms, lab results, and side effects determine whether your dose is working—or needs adjustment. Some men respond immediately, while others need a few weeks of fine-tuning.

Signs You May Need a Dose Adjustment

Your TRT dose may need to be re-evaluated if you experience:

  • Persistent fatigue or low libido

  • Acne or oily skin

  • Mood swings or irritability

  • Fluid retention or bloating

  • Reduced sexual performance

  • Anxiety or difficulty sleeping

Your provider will use a combination of lab testing and symptom tracking to optimize your treatment plan.

How ManUP Testosterone Clinic Gets Dosage Right

At ManUP Testosterone Clinic, we build customized testosterone therapy plans that evolve with you. Your dosage isn’t set in stone—we monitor, adjust, and optimize until we find the right balance.

Our process includes:

  • A full health history review and physical exam

  • Comprehensive lab panel to test total and free testosterone, estrogen, red blood cell count, and more

  • Personalized dosage recommendations based on your lifestyle and goals

  • Regular follow-ups and lab work to adjust dosage as needed

You’ll never be left guessing. We make sure your treatment is safe, effective, and tailored to your body.

Serving Missouri with 5 Convenient Locations

Visit one of our trusted men’s health clinics:

  • O’Fallon, MO

  • St. Peters, MO

  • Ellisville, MO

  • Fenton, MO

  • Washington, MO

Schedule Your Consultation Today

If you’re ready to stop feeling tired, unmotivated, or unlike yourself, let’s talk. With the right TRT dosage, you can regain your energy, improve your focus, restore your drive, and feel like the best version of yourself.

Call: 636-272-8894
Website: www.manup-testosterone.com
Take the first step. Reclaim your health. ManUP.