Ipamorelin is a GH secretagogue, which means that it promotes the secretion of GH into the bloodstream from the pituitary gland. Similar to GHRPs, is also an agonist of the ghrelin/growth hormone secretagogue receptor.

Ipamorelin mainly functions in both the brain and liver, which makes it unique in the world of age prevention and youth recovery. In the brain, studies in animal subjects demonstrated that it stimulates the pituitary gland, which is a pea-shaped gland located at the bottom of the hypothalamus in the base of the brain.

Unlike HGH , Ipamorelin is affordable, and does not have the negative side effects of HGH.

The primary function of the pituitary gland is to secrete specific hormones to regulate multiple endocrine system-related processes, including:

• Growth and metabolism
• Pain relief
• Temperature regulation

In the liver, a related study using the same test subjects determined that ipamorelin induces a significant increase in the hepatic production of IGF-1 levels.

As discussed in detail above, hGH therapy involves the direct injection of synthetic HGH, which stimulates IGF-1 production in the liver. In contrast, sermorelin is a GH secretagogue that stimulates the secretion of endogenous GH and the resulting normal downstream processes including IGF-1 production.


Several studies have shown that the ability of ipamorelin to stimulate the pituitary gland and liver might elicit a number of physiological effects, including:

  • Strengthening the joints and connective tissue
  • Increasing the bone mass density and strength
  • Improving skin tone
  • Rejuvenating joints
  • Increased muscle mass
  • Increased sex drive
  • Improved recovery and repair from injuries
  • Increased adipose tissue (body fat) breakdown

What is CJC-1295?

CJC-1295 is a modified form for Growth Hormone -Releasing Hormone (GHRH) with improved pharmacokinetics, especially in regard to half life.

It is recommended to be taken at night to maximize the body’s natural cycle of growth hormone. As a result, it stimulates the pituitary gland during REM sleep.